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วารสารสมาคมจิตแพทย์แห่งประเทศไทย
Journal of the Psychiatrist
Association of Thailand
ISSN: 0125-6985
บรรณาธิการ มาโนช หล่อตระกูล
Editor: Manote
Lotrakul, M.D.
| NO: |
42714 |
| AU:
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อัมพร เบญจพลพิทักษ์ |
| TI:
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Acamprosate as an alternative
in the treatment of alcohol addiction |
| JN:
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ว.สมาคมจิตแพทย์แห่งประเทศไทย
(Journal of the Psychiatric Association of Thailand) 42,2 (เม.ย.-มิ.ย.
2540) 107-112 |
| AB:
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Problems of alcohol dependence
produce dramatic costs to society in terms of lost productivity,
social disorder and avoidable health care utilization. Based
on reasonable expectations of addiction treatments, clinical
trials have shown effectiveness of treatment strategies. Besides
psychosocial aspects, various studies have focused on neurotransmitter
and recepter systems that may be implicated in alcohol tolerance
and dependence. Acamprosate, a GABAergic agonist is one of the
relatively new drugs that yield promising result. This article
discusses the possible mechanisms of action of acamprosate as
well as reviews animal and human studies that support the use
of acamprosate in the treatment of alcohol dependence. |
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Copyright The
Psychiatric Association of Thailand. All Rights
Reserved.1999-2001